What’s the Difference Between Perimenopause, Menopause, and Postmenopause?
Vol. 1, No. 6
Date Published: 1 January 2025
Estimated Reading Time: 4 Minutes
This is the sixth installment in our multipart series on Aging. As we continue this journey, we hope you find this newsletter both inspiring and educational.
- Morgan Burns, APRN
Menopause is a natural stage in life that marks the end of reproductive years for women, but the journey through it involves distinct phases: perimenopause, menopause, and postmenopause. Understanding the differences between these stages can help women better navigate the changes and make informed decisions about their health.
Perimenopause: The Transition Phase
Perimenopause means "around menopause," and it refers to the transitional time leading up to menopause. This phase can begin as early as a woman’s mid-30s or 40s and typically lasts 4–8 years.
Key Features of Perimenopause:
- Hormonal Fluctuations: Estrogen and progesterone levels fluctuate, leading to irregular menstrual cycles.
- Symptoms: Common symptoms include hot flashes, night sweats, mood swings, sleep disturbances, and changes in libido.
- Fertility Declines: While pregnancy is still possible, fertility decreases significantly.
What to Do:
Managing symptoms during perimenopause may involve lifestyle changes, such as regular exercise, a balanced diet, and stress management. Hormonal therapies or supplements can help balance symptoms under a healthcare provider's guidance.
Menopause: The Milestone
Menopause is officially diagnosed after 12 consecutive months without a menstrual period, marking the end of a woman’s reproductive years. The average age for menopause in the United States is 51.
Key Features of Menopause:
- Hormone Levels Stabilize: Estrogen and progesterone production significantly decrease, often leading to more pronounced symptoms.
- Symptoms: Many symptoms of perimenopause, such as hot flashes and vaginal dryness, may persist or intensify. Other issues, like thinning hair and dry skin, may also arise.
What to Do:
Menopause is a good time to focus on long-term health, particularly bone density and cardiovascular health. Hormone Replacement Therapy (HRT) and other medical interventions may be considered to alleviate symptoms and reduce health risks.
Postmenopause: Life After Menopause
Postmenopause begins once a woman has gone an entire year without menstruating and lasts for the rest of her life. Hormone levels remain low during this time, and reproductive ability is permanently ceased.
Key Features of Postmenopause:
- Symptoms May Persist: Hot flashes and other menopausal symptoms may continue for several years but typically decrease over time.
- Health Risks Increase: With lower estrogen levels, women may be at greater risk for conditions such as osteoporosis and cardiovascular disease.
- Overall Wellness Focus: Many women find new energy in postmenopause and use this time to focus on their health and well-being.
What to Do:
Postmenopausal women should prioritize regular health checkups, bone density scans, and cardiovascular screenings. A diet rich in calcium and vitamin D and regular weight-bearing exercise, can help maintain bone and heart health.
How AZENA Health and Longevity Can Help
At AZENA Health and Longevity, we offer personalized support for every phase of menopause. Our services include:
- Hormone Replacement Therapy (HRT): Tailored solutions to alleviate symptoms and protect against long-term health risks.
- Peptides and Bioregulators: Innovative therapies to support cellular health and vitality.
- Inflammation Reduction: Managing inflammation to promote overall wellness and reduce the impact of hormonal changes.
Embrace Every Phase with Confidence
Navigating perimenopause, menopause, and postmenopause can feel overwhelming, but understanding the differences between these stages and taking proactive steps can make the journey smoother. At AZENA, we’re here to support you every step of the way. Visit azena.life to learn more about how we can help you thrive during this transformative time.
Anti-Aging Medicine
Modern science has provided greater insight into aging and many more tools to address it. At Azena, we view chronological age as a marker and benchmark to improve your biological age. Regardless of your chronological age, you’re never too young or old to feel younger and better. With our anti-aging and active aging programs, we help you manage and delay the effects of aging at any stage in life. Our mission is to help you look, feel, and function better—naturally.
Our comprehensive and individualized approach aims to place you ahead of the aging curve, reduce your biological age, and keep you functioning optimally—and feeling younger and better—for as long as you may live, and regardless of age.
When it comes to aging, don’t just survive, thrive! Let us partner with you in your health and wellness journey because life with function is more fun!
OurAIMD℠ approach sets us apart:
- AZENA
- Individualized
- Medical
- Directive

About the Author
Morgan Burns, APRN
Morgan is a Board-Certified Adult Gerontology Nurse Practitioner in private practice at AZENA Health & Longevity, and a former professional athlete.